A fixed point theorem for multi-maps satisfying an implicit relation on metrically convex metric spaces

In this paper, we give a fixed point theorem for multi-valued mapping satisfying an implicit relation on metrically convex metric spaces. This result extends and generalizes some fixed point theorem in the literature

Identification and distribution of anaerobic bacteria isolated from clinical specimens in a University Hospital: 4 years’ experience

Anaerobes, which are components of microbiota, can cause life-threatening infections. Because of their fastidious nature, they are difficult to isolate and are often overlooked. The goal of this study was to identify the anaerobic bacteria isolated from clinical specimens at the Central Laboratory of Hacettepe University Hospital in 2015-2018 and to evaluate the distribution of the isolated bacterial species among the different specimen types. The anaerobic bacteria isolated from the specimens were identified by the conventional methods and MALDI-TOF MS.Overall, 15,300 anaerobic cultures were studied. Of these, 14,434 (94.3%) were blood samples and 866 (5.7%) were other clinical specimens. A total of 138 anaerobic bacteria were isolated: 62 (44.9%) were isolated from blood samples and 76 (55.1%) from other specimens. The most isolated anaerobes from blood cultures were Bacteroides spp. (41.9%), followed by Cutibacterium acnes (25.8%) and Clostridium spp. (9.7%). The most isolated anaerobes from the other specimens were Gram-negative bacilli, including Bacteroides spp. (15.8%), Fusobacterium spp. (14.5%), Prevotella spp. (14.5%), and Porphyromonas spp. (2.6%). Anaerobic Finegoldia magna represented the major species among the isolated Gram-positive bacteria (10.5%). Anaerobic growth was observed in 0.4% of all the blood cultures and in 5.8% of the positive blood cultures. The results of our study showed that the incidence of anaerobic bacteremia was stable during the 2015-2018 period.Anaerobes, which are components of microbiota, can cause life-threatening infections. Because of their fastidious nature, they are difficult to isolate and are often overlooked. The goal of this study was to identify the anaerobic bacteria isolated from clinical specimens at the Central Laboratory of Hacettepe University Hospital in 2015-2018 and to evaluate the distribution of the isolated bacterial species among the different specimen types. The anaerobic bacteria isolated from the specimens were identified by the conventional methods and MALDI-TOF MS.Overall, 15,300 anaerobic cultures were studied. Of these, 14,434 (94.3%) were blood samples and 866 (5.7%) were other clinical specimens. A total of 138 anaerobic bacteria were isolated: 62 (44.9%) were isolated from blood samples and 76 (55.1%) from other specimens. The most isolated anaerobes from blood cultures were Bacteroides spp. (41.9%), followed by Cutibacterium acnes (25.8%) and Clostridium spp. (9.7%). The most isolated anaerobes from the other specimens were Gram-negative bacilli, including Bacteroides spp. (15.8%), Fusobacterium spp. (14.5%), Prevotella spp. (14.5%), and Porphyromonas spp. (2.6%). Anaerobic Finegoldia magna represented the major species among the isolated Gram-positive bacteria (10.5%). Anaerobic growth was observed in 0.4% of all the blood cultures and in 5.8% of the positive blood cultures. The results of our study showed that the incidence of anaerobic bacteremia was stable during the 2015-2018 period

Determination of vitamin B9 levels in the milk of Brown Swiss and Simmental cows using the ELISA method

The aim of this study was to determine the levels of folic acid in Brown Swiss and Simmental cows’ milk by the competitive ELISA method. Brown Swiss and Simmental cows’ milk samples were collected from two dairies between  February and August 2017 (20 samples from Brown Swiss and 22 samples  from Simmental). The average level of vitamin B9 in Brown Swiss milk was approximately 3.27 ± 1.23 μg/100 g, while for Simmental it was around 2.99 ± 0.88 μg/100 g. In the milk mixture, the mean folic acid level was 3.13 ± 1.07 μg/100 g. There was no statistical difference between breeds in terms of folic acid levels in cow's milk. It was concluded that milk is not a sufficient source to meet the daily folic acid needs of adults in Turkey.Keywords: Dairy cattle breeds, folic acid, raw mil

Emergence of structure in mouse embryos: Structural Entropy morphometry applied to digital models of embryonic anatomy

We apply an information-theoretic measure to anatomical models of the Edinburgh Mouse Atlas Project. Our goal is to quantify the anatomical complexity of the embryo and to understand how this quantity changes as the organism develops through time. Our measure, Structural Entropy, takes into account the geometrical character of the intermingling of tissue types in the embryo. It does this by a mathematical process that effectively imagines a point-like explorer that starts at an arbitrary place in the 3D structure of the embryo and takes a random path through the embryo, recording the sequence of tissues through which it passes. Consideration of a large number of such paths yields a probability distribution of paths making connections between specific tissue types, and Structural Entropy is calculated from this (mathematical details are given in the main text). We find that Structural Entropy generally decreases (order increases) almost linearly throughout developmental time (4–18 days). There is one `blip’ of increased Structural Entropy across days 7–8: this corresponds to gastrulation. Our results highlight the potential for mathematical techniques to provide insight into the development of anatomical structure, and also the need for further sources of accurate 3D anatomical data to support analyses of this kind

Using Sat solvers for synchronization issues in partial deterministic automata

We approach the task of computing a carefully synchronizing word of minimum length for a given partial deterministic automaton, encoding the problem as an instance of SAT and invoking a SAT solver. Our experimental results demonstrate that this approach gives satisfactory results for automata with up to 100 states even if very modest computational resources are used.Comment: 15 pages, 3 figure

Çoruh vadisi fıstıkçamı orman ekosistemlerine ilişkin bitki örtüsü ve bazı fiziksel ve kimyasal toprak özelliklerinin incelenmesi

Bir Akdeniz bitki örtüsü olan fıstıkçamı Doğu Karadeniz Bölgesinde Trabzon- Söğütlü Deresi ve Artvin-Çoruh Vadisinde dar bir alanda yayılış göstermektedir. Koruma amaçlı ayrılması gereken bu alanlarda fıstıkçamının kalıcılığının sağlanmasında toprak etmenlerinin önemi büyüktür. Bu çalışmada Çoruh vadisi fıstıkçamı meşcerelerinden 8 adet toprak profili alınmıştır. Alınan toprak örneklerinin tekstür, pH, organik madde ve taşlılık oranları belirlenmiştir. Toprak pH’sı 6.3 ile 7.04, toprak organik maddesi ise 0.7 ile 8.1 arasında değişmiştir. Toprağın taşlılık oranı yüksek olup, horizonlaşma zayıftır. Meşcere kapalılığı zayıf olup yoğun diri örtü doğal gençleşme şansını azaltmıştır. Koruma altına alınmadığı takdirde buradaki fıstıkçamı meşcerelerinin yok olması kaçınılmaz görünmektedir.Stone pine (Pinus pinea L.), a mediterranian species, locally spreads in two locations of Eastern Blacksea Region: Tarbzon-Söğütlü Watershed and Artvin-Coruh Watershed. Understanding soil properties of these areas will be useful in preserving them. In this study 8 soil pits were dug in stone pine stands along Coruh Valley. Soil texture, soil organic matter content and soil pH were determined. Soil pH ranged from 6.3 to 7.04; soil organic matter content changed from 0.7 to 8.1. Coarse fragment content of soil were very high. Stand canopy was low and natural regeneration of stone pine were decreased by dense understory cover. It seems these stone pine stands will disappear if the necessary measures were not taken

Speaker-independent emotion recognition exploiting a psychologically-inspired binary cascade classification schema

In this paper, a psychologically-inspired binary cascade classification schema is proposed for speech emotion recognition. Performance is enhanced because commonly confused pairs of emotions are distinguishable from one another. Extracted features are related to statistics of pitch, formants, and energy contours, as well as spectrum, cepstrum, perceptual and temporal features, autocorrelation, MPEG-7 descriptors, Fujisakis model parameters, voice quality, jitter, and shimmer. Selected features are fed as input to K nearest neighborhood classifier and to support vector machines. Two kernels are tested for the latter: Linear and Gaussian radial basis function. The recently proposed speaker-independent experimental protocol is tested on the Berlin emotional speech database for each gender separately. The best emotion recognition accuracy, achieved by support vector machines with linear kernel, equals 87.7%, outperforming state-of-the-art approaches. Statistical analysis is first carried out with respect to the classifiers error rates and then to evaluate the information expressed by the classifiers confusion matrices. © Springer Science+Business Media, LLC 2011

A cost effectiveness analysis of salt reduction policies to reduce coronary heart disease in four Eastern Mediterranean countries.

BACKGROUND: Coronary Heart Disease (CHD) is rising in middle income countries. Population based strategies to reduce specific CHD risk factors have an important role to play in reducing overall CHD mortality. Reducing dietary salt consumption is a potentially cost-effective way to reduce CHD events. This paper presents an economic evaluation of population based salt reduction policies in Tunisia, Syria, Palestine and Turkey. METHODS AND FINDINGS: Three policies to reduce dietary salt intake were evaluated: a health promotion campaign, labelling of food packaging and mandatory reformulation of salt content in processed food. These were evaluated separately and in combination. Estimates of the effectiveness of salt reduction on blood pressure were based on a literature review. The reduction in mortality was estimated using the IMPACT CHD model specific to that country. Cumulative population health effects were quantified as life years gained (LYG) over a 10 year time frame. The costs of each policy were estimated using evidence from comparable policies and expert opinion including public sector costs and costs to the food industry. Health care costs associated with CHDs were estimated using standardized unit costs. The total cost of implementing each policy was compared against the current baseline (no policy). All costs were calculated using 2010 PPP exchange rates. In all four countries most policies were cost saving compared with the baseline. The combination of all three policies (reducing salt consumption by 30%) resulted in estimated cost savings of $235,000,000 and 6455 LYG in Tunisia;$39,000,000 and 31674 LYG in Syria; $6,000,000 and 2682 LYG in Palestine and$1,3000,000,000 and 378439 LYG in Turkey. CONCLUSION: Decreasing dietary salt intake will reduce coronary heart disease deaths in the four countries. A comprehensive strategy of health education and food industry actions to label and reduce salt content would save both money and lives

Combined effect of steel fibres and steel rebars on impact resistance of high performance concrete

The investigation on the impact properties of normal concrete (NC)and reinforced concrete (RC) specimens, steel fibre reinforced concrete (SFRC) specimens and RC+SFRC specimens with different steel fibres dosages were carried out with the drop-weight impact test recommended by ACI Committee 544. The results indicate that the number of blows to final failure greatly increased by addition of steel fibres. Moreover, the combination of steel fibres and steel rebars demonstrates a significant positive composite effect on the impact resistance, which results on the improvement in impact toughness of concrete specimens. In view of the variation of impact test results, the two-parameter Weibull distribution was adopted to analyze the experimental data. It is proved that the probabilistic distribution of the blows to first crack and to final failure of six types of samples are approximately two-parameter Weibull distribution.Funded by the National Natural Science Foundation of China (NSFC) (Grant No.50578026)Financial support provided by the Research Center of Mathematics of the University of Minho through the FCT Pluriannual Funding Progra